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HONOURs

HONOURs is an EU-financed Marie Skłodowska-Curie Action (MSCA) training network on host switching pathogens, infectious outbreaks and zoonosis. The objective of HONOURs is to train Early Stage Researchers (ESRs) in all aspects of infectious outbreaks. The consortium consists of 10 high profile universities, research institutions and companies. Coordination is at the Academic Medical Center of the University of Amsterdam. The partners are located in Belgium, Germany, the Netherlands, Spain, Switzerland and the United Kingdom.

Why HONOURs?

The ongoing increase of the human population accompanied by growing numbers of livestock to feed this population, as well as human invasion into natural habitats of wild animals makes humans and animals progressively vulnerable to host-switching pathogens. Global trade as well as climate changes can contribute to pathogen transmission, e.g. through import of infected vectors or expansion of habitats for arthropod vectors such as mosquitoes and midges.

Preparedness needs training

Preparedness needs expertise in many areas. At surveillance sites early detection and identification of viruses involved in outbreaks is crucial. Screening of different animal species and humans who have been in close contact with (diseased) animals for known or yet undiscovered viruses will also aid preparedness. Novel viruses in these populations will have to be evaluated for their pathogenicity in susceptibility studies.

The HONOURs network will generate new health and scientific knowledge with the aim to locate, identify, characterize, contain, and control infections that are caused by zoonotic agents. HONOURs will provide training to 15 promising young researchers at the interface of veterinary and human health, virology, biostatistics, and pathogen discovery. These early stage researchers will become “preparedness- experts”.

About HONOURs organisation

HONOURs ESR REUNION IN AMSTERDAM!

       1 reunion group foto

On the 12th of November the ESRs had their first HONOURs reunion meeting in Amsterdam.

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PhD DEFENCE TIM PASSCHIER!

       TIM defense

On the 8th of November 2022, Tim Passchier successfully defended his thesis at the University of Leeds, UK, entitled: ‘’Elucidation of the Hendra henipavirus nucleocapsid protein structure and its genome encapsidation architectures’’. He presented his findings on recombinant expression and purification of the viral nucleoprotein and its structural resolution through cryo-electron microscopy, identifying established and novel protein-protein and protein-RNA interactions.

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Tim Passchier wins the Rigaku 20 minute talk prize!

       TIM PRIJS I

Tim Passchier has won the Riguka prize at the “Proteins by Candlelight” meeting. A Northern Structural Biology meeting, 25-26 October 2022 at the University of York. Thanks to CCP4, providing Software for Macromolecular X-Ray Crystallography, this was a free meeting for early career structural biologists.

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PhD DEFENCE CEREN ŞIMŞEK!

       Ceren thesis defence DEZE als eerste

The 25th of January 2022 at 4pm, Ceren Şimşek successfully defended her thesis at the University of Leuven, Belgium, entitled: “ROTAVIRUS IN BATS AND HUMAN. Genetic diversity and gastroenteritis in the post-vaccine era”. She presented her research on the genetic diversity of rotaviruses collected in bats around the world, contributing evidence for interspecies transmission events of rotaviruses from bats to humans and other animals.

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PhD DEFENCE MITRA GULTOM!

       Mitra party

On the 21th of December 2021 Mitra Gultom defended her thesis entitled “Development of airway epithelial culture models for the characterization of emerging respiratory viruses in human and animal reservoirs”. She presented the repository of well-differentiated airway epithelial cell cultures from various domesticated and wildlife animal species, and the power of these cultures to investigate coronaviruses.

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PhD DEFENCE JOAN MARTI CARRERAS!

       Joan verwijzing midden

The 20th of December 2021 Joan Marti Carreras defended his thesis entitled “Third generation sequencing and diversity of herpesviruses”. Herpesviruses have complex, large size genomes and Joan Marti Carreras presented powerful new techniques to sequence and characterize these viruses. Furthermore the VANIR pipeline was explained in a clear presentation that could be followed live or via livestreaming.

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PhD DEFENCE PAULINE DIANNE SANTOS!

 

       Pauline defense

On the 28th of October 2021 Pauline Dianne Santos successfully defended her thesis entitled “High-throughput sequencing based early warning and outbreak investigation”. The defence was open to the public, with Pauline presenting the result of her research: the elegant Early Warning System she developed, the detection of West Nile virus and Usutu virus and the discovery of novel viruses in birds.

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PhD DEFENCE TRAN THI NHU THAO!

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On the 23rd of June 2021 Tran Thi Nhu Thao defended her PhD-thesis entitled “Establishment of a reverse genetics platform for emerging RNA viruses”. Thao presented the power of a universal reverse genetics platform for the assembly and engineering of infectious full-length cDNA clones of viruses.

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PhD DEFENCE ALEXIS HOSTE!

       AH celebration

On the 16th of April 2021 Alexis Hoste defended his thesis. The defense lasted 3 hours with

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PhD DEFENCE KEVIN SZILLAT!

       Kevin Defense

On the 3rd of February 2021 Kevin Szillat successfully defended his PhD thesis entitled "Virus characterisation in an era of outbreaks"

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PhD DEFENCE BEATRIZ ÁLVAREZ RODRIGUEZ!

       BEA promotie

The 17th of November 2020 Beatriz Álvarez Rodriguez successfully defended her PhD thesis entitled "Nairovirus nucleoproteins: development of diagnostic tools, structural characterisation and functional studies".

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PhD DEFENCE JOYCE ODEKE AKELLO!

       Joyce PhD

On 21st of October 2020 Joyce Odeke Akello successfully defended her thesis: “Identification and Characterisation of Emerging Viruses from Clinical and Environmental Samples”.

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HONOURs

Host switching pathogens, infectious outbreaks and zoonosis; a Marie Sklodowska-Curie Innovative Training Network.

This project has received funding from the European Union's Horizon 2020 research and innovation programme under grant agreement No 721367.